Orphen and his gang has set out on an all new adventure with many monsters to battle and no peace and quiet. But a new friend has joined the group. Her name Lycorus who was sent to find Orphen. Many mysterious shadows are overhanging over head. (Source: ANN)

Amawa Hibiki is a young man just out of college, with an education to be an athletics teacher. He's been having a hard time finding a job since he graduated, so all his money has gone towards living expenses. When his landlady demands his first payment to live in her living establishment upfront, he heads to the local middle school to get hired as a teacher. However, the principal refuses to hire him without hesitation. She will not hire men as teachers and makes it clear that she hates all men, saying they put no love into their passions and work. Amawa does not give up and with the help of his landlady, he crossdresses as a woman without a second thought, and gets hired, so he can earn money and also prove the principal wrong. Now, he has to keep his real gender a secret, and avoid strange situations, including the affections of his students (from both genders).

Yui is an average schoolgirl who lives in a future where all computers are supported by a single global network known as COMNET. Yui is a computer-illiterate girl who after a computer-lab accident is approached by IR, a raccoon looking corrector computer program, which tells her she must save COMNET. She must stop the rogue A.I. (Artificial Intelligence) computer program known as Grosser and his hench-programs from taking over the world. Grosser was originally designed to be that manager of all of COMNET. At first she's very reluctant to play the heroine because of her complete lack of knowledge and ability with computers. To save COMNET she must find and gain the trust of the other seven wayward corrector programs. They must also find the creator or COMNET Professor Inukai, to help stop Grosser for good.

Although cheerful and delicate, Sakura Sakurakouji is a skilled martial artist with a sense of fairness that never falters—no matter the situation. Upon witnessing people burning in blue flames while on a bus ride home, she calls the police to bring their murderer to justice only to find that no evidence remains. However, all her doubts about what she saw vanish when the next day, the new transfer student Rei Oogami joins her class; he is the very boy she watched commit murder in cold blood. Rei is kind, sweet, and quickly becomes popular, contradicting Sakura's accusations. Soon enough, she learns his true nature: a Code Breaker, or "one who does not exist." To Sakura's shock, Rei—armed with mysterious powers—seeks to exact justice according to the principle of "an eye for an eye." Determined to bring Rei to the right path, Sakura keeps close to him in the hopes of redeeming him from his ways before others are hurt. [Written by MAL Rewrite]