The story follows the aloof supreme lord of the myriad realms. He handpicks young girls, each with the potential to ascend as future deities, and embarks on a treacherous quest to reshape the destiny of the realms. Confronting formidable challenges and obstacles, will these fledgling girls triumph in their trials and forge a new world from the ashes of the old?

Kaiji Itou is a good-for-nothing loiterer who spends his days drinking beer and stealing hubcaps—that is, until he ends up being tricked by his former co-worker. Unable to suddenly repay his friend's huge debt all by himself, Kaiji is offered a shady deal to participate in an illegal underground gamble on a cruise ship. This turns out to be nothing more than the beginning of his new life of hell—thrown headlong into a life-threatening roller coaster of mind games, cheating, and deceit. Based on the first entry of the famous gambling manga series by Nobuyuki Fukumoto, Gyakkyou Burai Kaiji: Ultimate Survivor follows our unlucky protagonist as he is forced to fight not only other people, but also the mysteries of their psyches. Kaiji finds out the hard way that the worst sides of human nature surface when people's backs are against the wall, and that the most fearsome dangers of all are greed, paranoia, and the human survival instinct itself.

In times of need, if you look in the right place, you just may see a strange telephone number scrawled in red. If you call this number, you will hear a young man introduce himself as the Yato God. Yato is a minor deity and a self-proclaimed "Delivery God," who dreams of having millions of worshippers. Without a single shrine dedicated to his name, however, his goals are far from being realized. He spends his days doing odd jobs for five yen apiece, until his weapon partner becomes fed up with her useless master and deserts him. Just as things seem to be looking grim for the god, his fortune changes when a middle school girl, Hiyori Iki, supposedly saves Yato from a car accident, taking the hit for him. Remarkably, she survives, but the event has caused her soul to become loose and hence able to leave her body. Hiyori demands that Yato return her to normal, but upon learning that he needs a new partner to do so, reluctantly agrees to help him find one. And with Hiyori's help, Yato's luck may finally be turning around. [Written by MAL Rewrite]