A magician, a female doctor, a gangster, an archaeology professor, a policewoman, a drug dealer, a businessman... Such a random group of people find themselves trapped on a desolate island when they wake up from sleep one day. They are surrounded by tribes, mutant viruses, and countless life and death situations on this mysterious island. What will they do to survive and escape?

Maiku Kamishiro's past has always been somewhat of a mystery to him. The only clue he has to who his family might be is an old photograph showing two young children, a boy and a girl, playing in a small pool outside of a blue house. In an attempt to find his family, he moves to this blue house and begins working as a programmer. He's living a comfortable life until the day two very different girls show up at his door, both in possession of the same photograph, and both claiming to be his twin. With no way to prove who is a relative and who is a stranger, Maiku allows both girls to move in with him until they know for sure. 

(Source: ANN)

Saeki Koushirou works as a wedding planner, but his own love life is in shambles. His background makes it difficult for him to commit himself wholeheartedly to love. The child of a divorced couple, he lives with his father. He has a mother and a sister, but he has not seen them in years. After being dumped by his girlfriend, a chance encounter with a female high school student shakes Koushirou's calm and awakens new feelings in him—but he learns that the girl is in fact his sister, who will now be staying with his father and him. Yet, the feelings in Koushirou's heart... (Source: ANN)

The once peaceful city-state of Lisvalletta has found itself beset by a dangerous new drug called Anthem. The side effects of the drug allow the user to enter a state of Overdrive, wherein they mutate into superpowered beasts with inhuman abilities. With the police powerless to stop this new threat, the responsibility falls upon the Special Crime Investigation Unit SEVEN-O. To offset the dangers of this work, the investigators work under the patented "Double Decker" system, which requires them to team up in "buddy cop" pairs. As a child, average police officer Kirill Vrubel fantasized about being a hero who would save his school from a random terrorist attack. His chance to be a hero arrives when his landlady blackmails him into searching for her lost cat. Upon arriving and falling asleep in an abandoned warehouse, Kirill finds himself in the middle of a hostage situation involving an Anthem user. By teaming up with SEVEN-O detective Douglas "Doug" Bilingam, Kirill earns his spot as the newest member of SEVEN-O. Now, with the help of this secret organization, he may finally achieve his dream of becoming a hero. [Written by MAL Rewrite]