Vanquished Queens OVAs depict what happened to various characters who were absent in Queen's Blade: Rebellion and what happened to them after Queen's Blade: Utsukushiki Toushitachi.

Shinichi Chiaki is a first class musician whose dream is to play among the elites in Europe. Coming from a distinguished family, he is an infamous perfectionist—not only is he highly critical of himself, but of others as well. The only thing stopping Shinichi from leaving for Europe is his fear of flying. As a result, he's grounded in Japan. During his fourth year at Japan's top music university, Shinichi happens to meet Megumi Noda or, as she refers to herself, Nodame. On the surface, she seems to be an unkempt girl with no direction in life. However, when Shinichi hears Nodame play the piano for the first time, he is in awe of the kind of music she creates. Nevertheless, Shinichi is dismayed to discover that Nodame is his neighbor, and worse, she ends up falling head over heels in love with him. [Written by MAL Rewrite]

Following his brave sacrifice in the war against Albion, Saito Hiraga is knighted and treated as an aristocrat, something that proves difficult for Louise Françoise Le Blanc de La Vallière. With their relationship no longer defined as the mighty Void mage and clueless familiar, she wonders what exactly this means for them. While venturing to a castle, Louise is ambushed by a powerful mage named Sheffield. Battling alone, the young mage nearly faces defeat until Saito makes his appearance. The mystical and unknown nature of Void magic seems to be at work in the battle, and Louise begins to believe in the possibility of another Void user. Moreover, she realizes that Saito's magical rune is fading, and so a new adventure begins as they search for the elf who revived Saito in the past. The relationship between former master and servant faces a new challenge as they work to restore the runes and redefine the bond which holds them together. [Written by MAL Rewrite]

Mikoto Misaka and her friends are back, investigating rumors across Academy City. Soon, Mikoto discovers something terrifying: horrific experiments are taking place throughout the city, involving the murder of thousands of espers. Moreover, these espers are far from just ordinary people: they are clones of Mikoto herself. Feeling responsible for their treatment, she sets off to put an end to the experiments; however, the forces opposing her are much more dangerous than she anticipated, and Mikoto finds herself up against some of the most powerful espers imaginable. Toaru Kagaku no Railgun S continues the story of the Railgun as she desperately fights to put an end to the inhuman experiments that she believes she helped cause, her life dragged deep into despair in the process. There's never a dull moment in Academy City, but no one ever said all of them would be pleasant. [Written by MAL Rewrite]